1. Pertaining of someone being malicious, malignant, offensive, or showing ill will and a desire to hurt others: "The news on TV told about a high school student who was planning a despiteful attack on fellow students by using explosives and a gun to kill his parents and fellow classmates at his school; however, he was apprehended by the police because he was revealing his plans on one of the social websites on the internet."
2. Etymology: from Middle English, originally used as a noun, "contempt, scorn" as in the phrase in despite of; from Old French despit; from Latin despectus, "looking down on"